Biostimulating fillers contain special substances that, when injected under the skin, stimulate fibroblast cells to increase collagen and elastin production.
The goal is not to provide immediate volume, but to improve the structural quality of the skin over time.
In short:
- Classic filler: Provides immediate volume.
- Biostimulating filler: Gradually increases the skin’s own volume and firmness over time.
Different Types of Biostimulating Fillers and Their Areas of Use
Each product has a different composition and effect. Therefore, the choice of filler is determined based on criteria such as skin type, age, target area, and desired outcome.
| Product Composition | Effect | Preferred Indications |
|---|---|---|
| Calcium Hydroxylapatite (CaHA) – like Radiesse® | Strongly stimulates collagen synthesis. Provides a mild lifting effect. | Mid-to-lower face sagging, jawline definition, hand rejuvenation |
| Poly-L-Lactic Acid (PLLA) – like Sculptra® | Stimulates collagen production over the long term, with results developing gradually. | Overall facial volume loss, tired appearance, thinning of the skin |
| Polycaprolactone (PCL) – like Ellansé® | Provides both volumizing and biostimulatory effects, with results lasting 2–3 years. | For moderate to severe volume loss, enhancing the facial contour |
| Amino Acid and Polynucleotide-Based Stimulators – Next-Generation Meso-Fillers | Supports cell regeneration and moisture balance. | Improving skin quality, fine wrinkles, neck and décolleté rejuvenation |
Post-Procedure Process: Changes Observed Over Time
The effects of biostimulating fillers appear gradually. Although they vary from person to person, the general process is as follows:
| Time Frame | Observed Changes |
|---|---|
| 1–7 days | Mild plumping sensation, refreshed skin appearance. |
| 2–4 weeks | Collagen production begins, and the skin tissue becomes firmer. |
| 6–12 weeks | Skin elasticity and radiance increase, and the lifting effect becomes more noticeable. |
| 6–18 months | The effect reaches its maximum; it can be prolonged with regular care and a healthy lifestyle. |
Advantages
- Increases the skin’s natural regenerative capacity.
- Provides long-lasting and gradual results.
- Maintains facial contours for a natural appearance.
- Improves skin quality in addition to adding volume.
Complications and Considerations
When performed with proper patient selection and correct technique, biostimulating fillers have a high safety profile.
Temporary and mild effects may include:
- Mild swelling, redness, or tenderness at the treatment site
- Rarely, small bruises
These effects usually resolve spontaneously within a few days.
With sterile working conditions and application by an experienced surgeon, the risk of serious complications is extremely low.
Frequently Asked Questions
What is the difference between biostimulating fillers and classic fillers?
Classic fillers add volume; biostimulating fillers provide long-term rejuvenation by increasing the skin’s own collagen production.
How soon are the results visible?
Skin vitality and firmness are usually noticeable within 1–2 months, with the full effect becoming evident around the 3rd month.
How many sessions are required?
Depending on the product used, 1 to 3 sessions may be planned. For some products, a single application is sufficient.
How long do the results last?
Depending on the product, results typically last between 12–24 months and can be repeated at regular intervals.
How soon can I return to daily life?
Most people can return to their social activities immediately after the procedure. Mild swelling or redness usually subsides within 1–2 days.
Result: A Natural, Long-Lasting, and Personalized Rejuvenation Approach
Biostimulating fillers are among the most up-to-date and scientifically based approaches in modern aesthetic medicine.
The goal is not only to change the appearance, but to rebuild the skin’s own healthy structure.
With proper patient selection and correct product planning, the results are natural, long-lasting, and satisfying.
